Tanti auguri HAART!

[Barney]

...e con oggi sono 20! 20 anni di cure quotidiane, di gioie e dolori, di aspettative non più disattese, di vite salvate.

'The "decade of HAART" began with the 11th International Conference on AIDS in Vancouver, British Columbia, July 7-16, 1996. During that Conference, David Ho, MD, of the Aaron Diamond AIDS Research Center, New York, NY, and George Shaw, MD, PhD, of the University of Alabama at Birmingham School of Medicine, presented viral dynamics data showing that the average person with HIV infection produced 10 billion virions/day, bringing into sharp focus the fact that this was a viral infection that required antiviral treatment. (This seems painfully obvious now, but it was not at the time.) John Mellors, MD, of the University of Pittsburgh, Pittsburgh, Pennsylvania, also presented data showing that HIV viral load predicted progression as well as CD4+ cell decline rates, and the HIV viral load test with a threshold of detection at 15-25 copies/mL was introduced. Perhaps most important were the studies of: (1) "triple-drug therapy" using nevirapine-based treatment, described by Julio Montaner, MD, of the British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, Vancouver, Canada; (2) triple-drug therapy with indinavir-based treatment, described by Roy Gulick, MD, from New York University School of Medicine, New York, NY; and (3) the potential benefit of ritonavir in boosting saquinavir, described by Martin Markowitz, MD, from the Aaron Diamond AIDS Research Center, New York, NY. This group of observations converged to initiate a decade of progress against an important disease that is truly extraordinary in terms of the intensity of the effort and the progress achieved. Together, they constituted what is often considered to be the beginning of the HAART era.'

[uffa2]

l'articolo da cui Barney ha estratto questo passaggio è qui: http://www.medscape.org/viewarticle/523119

[skydrake]

E giusto per far vedere l'impatto dell'HAART sul tasso di mortalità dei sieropositivi: